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KMID : 0358420120550050343
Korean Journal of Obstetrics and Gynecology
2012 Volume.55 No. 5 p.343 ~ p.347
Primary malignant melanoma of the uterine cervix: A case report
Yun Nae-Ri

Park Jung-Woo
Park Jee-Hyun
Choi Suk-Jin
Hwang Sung-Ook
Abstract
After the discovery of melanocytes in the cervix in 1959, it was recognized that primary malignant melanoma of the cervix exists as a separate entity. A 74-year-old woman visited hospital for vaginal bleeding from a black colored cervical mass. The pathology of cervical punch biopsy showed a malignant melanoma with positive immnunohistochemical stainings for S100 protein and HMB-45 antibody. Abdominal radical hysterectomy with pelvic and paraaortic lymphadenectomy was performed. The final pathology was a malignant melanoma of the cervix with metastases for both external iliac lymph nodes and tumor involvement in the margin of vaginal resection. She received cisplatin based concurrent chemoradiotherapy postoperatively. But 6 months later, she received another chemotherapy with dacarbazine and cisplatin for recurrence. We report a case of a 74-year-old patient with a malignant melanoma of the uterine cervix with a brief review.
KEYWORD
Malignant melanoma, Uterine cervix, Vaginal bleeding
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